Plants such as rhodiola (Rhodiola rosea
) and ashwagandha (Withania somnifera
) belong to a class of flora with known anxiolytic (anti-stress) compounds. Salidroside is one of the adaptogenic substance extracted from Rhodiola rosea. Clinical trials demonstrate the therapeutic potential of this plant in easing anxiety, stress, fatigue, and depression .
Ashwagandha, commonly known as Indian ginseng, is demonstrated to have beneficial compounds that help with nervous, endocrine, and cardiopulmonary functions. It is a medicinal herb used for centuries due to its analgesic, anti-inflammatory, antimicrobial, and energy boosting properties 
. It is known as an adaptogen due to its anti-anxiety side effect .
These two herbs are found in combination with other herbal ingredients such as skullcap, hops, verbena, oats, valerian, chamomile, St. John's Wort, passionflower, and catnip to treat anxiety. These plants provide safe and non-synthetic support to boosting the neuroendocrine system's ability to cope with chronic anxiety, thus improving overall mood and wellbeing.