PureNature Ultra Calm
Exposure to chronic stress is linked with systemic oxidative stress that manifests as symptoms of anxiety. When ignored, it also leads to immune, digestive, and sleep impairments. Ultra Calm contains a proprietary blend of herbal extracts and essential nutrients that support a healthy mind and body.†
Ultra Calm is packed with natural ingredients that help with:†
- Stress-induced anxiety
- Sleep impairments
- Fatigue
- Focus
Learn More About Ultra Calm
PureNature Ultra Calm is an all-natural supplement formulated to support the neuroendocrine system's ability to recover from long-term exposure to mental stress. It contains a proprietary blend of 18 herbal extracts known to have anti-anxiety, antioxidant, and anti-inflammatory properties [1-24].†
What are the ingredients in Ultra Calm?
PureNature Ultra Calm is formulated with essential vitamins and minerals and a potent proprietary blend of naturally extracted herbal ingredients including:
Rhodiola rosea - a flowering plant that belongs to a group of medicinal herbs having adaptogenic substances; clinical trials demonstrate the therapeutic potential of this plant in easing anxiety, stress, and fatigue.†
Lutein - a natural antioxidant compound found in plants including marigold, spinach, broccoli sprouts, and the green microalga Chlorella protothecoides; it is a carotenoid pigment demonstrated to reduce psychological stress by relieving systemic oxidative stress associated with anxiety disorders.†
Ashwagandha - is demonstrated to have beneficial compounds that help with nervous, endocrine, and cardiopulmonary functions. It is a medicinal herb used for centuries due to its analgesic, anti-inflammatory, antimicrobial, and energy boosting properties.†
GABA - the most important inhibitory neurotransmitter that regulates nerve activities. It is linked to physiological and psychological processes in the central nervous system. Unbalanced levels of GABA in the human brain is linked to anxiety.†
How to take PureNature Ultra Calm?
Ultra Calm comes with 60 easy-to-swallow veggie capsules per bottle. We recommend taking 2 capsules daily, 20-30 minutes before your meals with a full glass of water.
Ultra Calm Potential Health Benefits:
- Works as a natural anti-anxiety†
- Could reduce stress and mood disorder†
- Improve sleep and reduce fatigue†
- Boost cognitive function, memory and focus†
- Powerful anti-oxidant and anti-inflammatory†
- Enhances immune and nervous system†
PureNature Ultra Calm is Safe and All-Natural*
We strive to provide our customers with safe and all-natural formulas. All our supplements are in accordance with Good Manufacturing Practices (GMP). All our products also carry a certificate of analysis from an independent third-party lab indicating that they are safe.†
Ultra Calm Ingredients
Rhodiola rosea
Rhodiola rosea is a flowering plant that belongs to a group of medicinal herbs having adaptogenic substances. Salidroside is one of the adaptogenic substance extracted from R. rosea. Clinical trials demonstrate the therapeutic potential of this plant in easing anxiety, stress, and fatigue [15] [16].†
Lutein
Lutein is a natural antioxidant compound found in plants including marigold, spinach, broccoli sprouts, and the green microalga Chlorella protothecoides. It is a carotenoid pigment demonstrated to reduce psychological stress by relieving systemic oxidative stress associated with anxiety [3].†
Ashwagandha
Ashwagandha (Withania somnifera), commonly known as Indian ginseng, is demonstrated to have beneficial compounds that help with nervous, endocrine, and cardiopulmonary functions. It is a medicinal herb used for centuries due to its analgesic, anti-inflammatory, antimicrobial, and energy boosting properties [24] It is known as an adaptogen due to its anti-anxiety side effect [18] [24].†
Chamomile
Chamomile (Matricaria chamomilla) has been prescribed in herbal medicine for symptoms of generalized anxiety disorder. It has been demonstrated to be therapeutic towards strengthening focus and alleviating restlessness, muscle tension, mood imbalances, and sleep impairments. Studies suggest that the flavonoid (natural pigments) present in chamomile has strong antioxidant and anti-inflammatory capabilities that have anti-anxiety side-effects [11].†
GABA
GABA, also known as gamma-aminobutyric acid, is the most important inhibitory neurotransmitter that regulates nerve activities. It is linked to physiological and psychological processes in the central nervous system. Unbalanced levels of GABA in the human brain is linked to anxiety. GABA supplements demonstrate anxiolytic effect by reducing neurotransmission thus reducing feelings of uneasiness and distress [17].†
Lemon balm
Lemon balm (Melissa officinalis) has been used in herbal medicine for centuries to help relieve imbalances in the central nervous system. It has a bioactive compound known as rosmarinic acid which is demonstrated to have a calming, mood stabilizing, concentration boosting, and memory enhancing effects. Rosmarinic acid’s inhibiting interaction with the GABA-ergic system is also shown to produce anti-anxiety side-effects [20].†
Skullcap
Skullcap (Scutellaria lateriflora), a plant in the mint family is administered as a sedative in herbal medicine to relieve anxiety disorders. It is ingested in the form of tea or dietary supplement. The scientific literature discusses its anti-bacterial, anti-viral, anti-thrombic, anti-inflammatory, and antioxidant capabilities. Skullcap’s flavonoids (baicalin and baicalein) are purported to have anti-anxiety effects due to its interaction with the GABA-ergic system which is responsible for inhibiting neurotransmission [1].†
Hawthorn
Hawthorn (Crataegus monogyna) is a berry producing plant utilized in herbal medicine. Compounds (amines, flavonoids, procyanidins, organic acids, tannins, and triterpene derivatives) naturally occurring in this plant demonstrate positive side effects on the cardiovascular and nervous systems. Hawthorn extracts are used to reduce nervousness and improve sleep [6].†
Bacopa
Bacopa (Bacopa monnieri), also known as Brahmi, is used in herbal medicine to relieve neuroendocrine imbalances. It is purported to have active compounds that boost brain functioning and regulate brain stress hormones, as well as antioxidant side effects that reduce oxidative stress. Clinical trial demonstrates the potential of Bacopa in enhancing cognitive functions among aging individuals [5].†
Magnolia
Magnolia (Magnolia officinalis) bark and seed cones are important in Chinese and Japanese herbal medicine. The plant has active compounds (e.g., magnolol, honokiol, 4-O-methylhonokiol, and obovatol) acknowledged to have antioxidant and anti-inflammatory qualities that are beneficial in relieving various disorders and diseases including, stress, and anxiety [12].†
Passionflower
The major phytoconstituents in passionflower (Passiflora incarnate) are flavonoids (e.g., apigenin, luteolin, quercetin, kaempferol, vitexin, etc.), as well as alkaloids, carbohydrates, essential oil, and amino acids that are beneficial to the human body. Although unspecified, the active ingredients in passionflower are known to have calming and anti-anxiety potentials. The compounds in this plant likely work together with the neurotransmitter inhibitor GABA to reduce anxiety [7].†
Valerian
Extract from valerian (Valeriana officinalis) roots is used as herbal medicine and reported to have anti-anxiety and calming side effects, as well as antioxidant and neuroprotective properties. The psychoactive molecules in valerian extract regulate GABA-ergic systems, a principle inhibiting neurotransmitter linked to anxiety and sleep disorder [14].†
L-Theanine
L-theanine is a compound that naturally occurs in green tea. In experimental studies, it has demonstrated an ability to reduce elevated systolic blood pressure from stressful stimuli. This systemic interaction results in the reduction of tension, anxiety, and fatigue [13].†
Oats
Oats (Avena sativa) is a staple grain beneficial for nervous system functioning. It contains phytochemicals such as avenanthramides, flavonoids, flavonolignans, triterpenoid saponins, sterols, and tocols. A study on the effects of oat extracts demonstrates increased concentration, learning, and alertness during stressful situations. It also has antioxidant and anti-inflammatory capabilities which can help with relieving oxidative stress [21].†
Macuna Pruriens*
Macuna pruriens, commonly known as velvet bean, is a vine plant with phytochemicals that interact with the neuroendocrine system. It contains a high concentration of levodopa, a dopamine precursor. Dopamine is a neurotransmitter which is linked to motivation and attention. Dietary supplements with velvet bean extract are shown to decrease heart rate, as well as increase motivation and confidence [8].†
St. John's Wort
St John’s Wort (Hypericum perforatum) is a common herbal ingredient. When ingested, extract from this plant is known to increase the availability of dopamine and norepinephrine. These neurotransmitters regulate mood. The bioactive compounds hypericin and hyperforin are linked with St. John’s Wort mood enhancing and anti-inflammatory side-effects [2].†
Hops
Hops (Humulus lupulus) decrease neural activities with its sedative capability. It is an ingredient typically combined with other herbal medicines such as passionfruit and valerian to relieve stress and sleep impairments. Naturally occurring ethanolic and CO2 extracts from hops are suggested to induce relaxation [19].†
5-HTP (Griffonia Seed Extract)
The serotonin precursor 5-HTP can be extracted from an African shrub known as Griffonia simpicifolia. Neurotransmitters and central nervous system chemicals (melatonin, dopamine, norepinephrine, and beta-Endorphin) are shown to increase with 5-HTP intake [8]. Melatonin regulate sleep and wakefulness [9], dopamine and norepinephrine regulate mood and behavior [2] [8], and the increase in levels of beta-Endorphins during stressful situations may relieve pain [10].†
Essential Vitamins and Minerals
Ultra Calm also contains B Vitamins (Vitamins B1,2,5,6), Niacin (B3), Biotin(B7), Calcium Carbonate, Magnesium Oxide, Zinc Oxide, and Potassium Gluconate. Vitamin B Complex and trace minerals such as magnesium and zinc work together to control oxidative stresses [22] and have shown to improve cognitive function and memory in aging individuals [4].†
Experience the Benefits of All-Natural Ultra Calm
We are confident about the quality of our products and offer our customers a 1-year full refund. If you are unsatisfied with your purchase, do not hesitate to reach out to our 24/7 customer service by dialing 1-888-457-6441. We have dedicated PureNature customer service agents to address your concerns.
Frequently Asked Questions
Does Ultra Calm contain natural ingredients?
Yes! Our formula is composed of natural ingredients from food and plant extracts.†
What is the recommended dose for Ultra Calm?
Take 2 capsules daily, 20-30 minutes before your meals with a full glass of water.
What are the benefits of PureNature Ultra Calm?
Ultra Calm contains herbal extracts that have anti-anxiety side-effects. With this formula, the neuroendocrine system is better equipped to recover from systemic oxidative stress that inevitably leads to mental health issues.†
What is Ultra Calm's return policy?
PureNature offers a 1-year (365 days) full refund from the date of purchase. We have a 24/7 customer service to assist our customers with any concerns. Please contact 1-888-457-6441 with any questions.
PureNature Ultra Calm
Exposure to chronic stress is linked with systemic oxidative stress that manifests as symptoms of anxiety. When ignored, it also leads to immune, digestive, and sleep impairments. Ultra Calm contains a proprietary blend of herbal extracts and essential nutrients that support a healthy mind and body.†
PureNature Ultra Calm is packed with natural ingredients that help with:
- Stress-induced anxiety†
- Sleep impairments†
- Fatigue†
- Focus†
Scientific Literature on Healthy Brain Function
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References Cited
There are numerous scientific papers on the benefits of the ingredients found in Ultra Calm. We have compiled some of the literature for your convenience.†
[5] Calabrese C., Gregory W.L., Leo M., Kraemer D., Bone K., Oken B. (2008). Effects of a Standardized Bacopa Monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly: a Randomized, Double-Blind, Placebo-Controlled Trial. J Altern Complement Med 6:707-13. doi: 10.1089/acm.2008.0018.
[6] Can O.D. , Ozkay U.D., Oztürk N, Oztürk Y. (2010). Effects of Hawthorn Seed and Pulp Extracts on the Central Nervous System. Pharm Biol 48(8):924-31. doi: 10.3109/13880200903305500.
[10] Hartwig, A. C. (1991). Peripheral beta-Endorphin and Pain Modulation. Anesthesia Progress, 38, 3.
[12] Lee Y.J., Lee Y.M., Lee C.K., Jung J.K., Han S.B., Hong J.T. (2011). Therapeutic Applications of Compounds in the Magnolia Family. Pharmacol Ther 2:157-76. doi: 10.1016/j.pharmthera.2011.01.010.
[13] Mancini E., Beglinger C., Drewe J., Zanchi D., Lang U.E., Borgwardt S. (2017). Green tea Effects on Cognition, Mood and Human Brain Function: A Systematic Review. Phytomedicine 34:26-37. doi: 10.1016/j.phymed.2017.07.008.
[16] Panossian, A., Wikman, G., Sarris, J. (2010). Rosenroot (Rhodiola rosea): Traditional Use, Chemical Composition, Pharmacology and Clinical Efficacy. Phytomedicine 17(7):481-93. doi: 10.1016/j.phymed.2010.02.002.
[17] Pham, H.P., Sun, Cuie, Chen, X., van den Oord, E.J.C.G., Neale, M., Kendler, K.S., and Hettema, J.M. (2009). Association Study Between GABA Receptor Genes and Anxiety Spectrum Disorders. Depression and Anxiety 26: 998-1003.
[18] Pratte, M.A., Nanavati, K.B., Young, V., and Morley C.P. (2014). An Alternative Treatment for Anxiety: A Systematic Review of Human Trial Results Reported for Ayurvedic Herb Ashwagandha (Withania somnifera). The Journal of Alternative and Complementary Medicine 20(12): 901-908. DOI: 10.1089/acm.2014.0177.
[20] Scholey, A., Gibbs, A., Neale, C., Perry, N., Ossoukhova, A., Bilog, V., Kras, M., Scholz, C., Sass, Mathias, and Buchwald-Werner, S. (2016). Anti-Stress Effects of Lemon Balm-Containing Foods. Nutrition 6: 485-4821. doi:10.3390/nu6114805.
[24] Wankhede, S., Langade, D., Joshi, K., Sinha, S.R, and Bhattacharyya, S. (2015). Examining the Effect of Withania somnifera Supplementation on Muscle Strength and Recovery: a Randomized Controlled Trial. Journal of the International Society of Sports Nutrition 12(43): 1-11. https://doi.org/10.1186/s12970-015-0104-9.
Disclaimer: †The information on this site has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Results in description and Testimonials may not be typical results and individual results may vary. All orders placed through this website are subject to acceptance, in its sole discretion.
**Individual Results May Vary. Results in testimonials are atypical and results will vary on individual circumstances. We recommend all products with a healthy diet & exercise.