The human body hosts a colony of beneficial bacteria that is responsible for many essential physiological processes. A destabilized microbiome leads to the development of various physical disorders and diseases that typically manifest in the gastrointestinal system [2]. To boost, protect, and promote your body's microbiome, PROBIO40 delivers 40 billions counts of probiotics from Lactobacillus and Bifidobacterium species.
PROBIO40 is packed with probiotics that:
PROBIO40 is an all-natural dietary supplement containing 40 billion counts of probiotics. Probiotics are good bacteria that facilitate digestion and cardiovascular functions [2][11]. Due to probiotics' acknowledged antioxidant and anti-inflammatory properties, regular consumption has beneficial effects in treating various physical disorders and diseases [1][8].
PureNature PROBIO40 contains 40 billion counts of probiotics (beneficial live bacteria) to enhance your gut microbiome. The strains of bacteria in our formula belong to two of the most studied genera of microorganisms (Lactobacillus spp. and Bifidobacterium spp.) [3].†
The probiotics in PureNature PROBIO40 is encased in acid-resisting capsules with seaweed extract (marine polysaccharide complex). This delivery system (MAKTREK Bi-Pass Technology) ensures that probiotics in our formula stay alive and potent. Only living probiotics are capable of performing metabolic, anti-inflammatory, and antioxidant side effects.†
PROBIO40 comes with 60 easy-to-swallow vegetarian capsules per bottle. We recommend taking 2 capsules daily, 20-30 minutes before your meals with a full glass of water.
When gut microbiome is thrown out of balance by a combination of factors including age, diet, environment, genes, and medication, our body may suffer from a range of health problems. In some cases, probiotics from ingested food may not be enough to support and maintain a healthy gut. Do you want to supplement your diet with higher concentrations of probiotics? Do you want to improve your digestive functions and overall health? PROBIO40 is right for you.
We strive to provide our customers with safe and all-natural formulas. Our manufacturing facility is FDA registered, and all our supplements are in accordance with Good Manufacturing Practices (GMP). All our products also carry a certificate of analysis from an independent third-party lab indicating that they are safe.†
Probiotics are beneficial live bacteria that when ingested have beneficial effects on the preexisting microbiome in the body. The colony of microorganisms in the body is essential in maintaining physiological processes, most notably the conversion of food to essential nutrients and transport of nutrients in the body. It aids in the synthesis of Vitamin K which plays a role in hemostasis (e.g., coagulation of blood and repair on damaged blood vessels) [2][11]. It also protects the gut from harmful pathogens by colonizing the mucus layer of the gastrointestinal tract in a process referred to as colonization resistance, thus boosting gut immune system [6][11]. Probiotics also have anti-inflammatory and antioxidant capabilities that address various diseases throughout the body [6][7]. Live bacteria are most numerous in the gastrointestinal tract. In fact, there exist approximately trillions of bacteria belonging to 1,000 different species and composing of 5,000 strains in our digestive system [2].
Imbalanced or impaired microbiota (i.e., dysbiosis) links to various digestive diseases and disorders including Crohn's disease, ulcerative colitis, irritable bowel syndrome (IBS), and Clostridium difficile colitis [1][6]. Dysbiosis is also linked to metabolic syndrome (e.g., hypercholesterolemia, hypertension, obesity and type-2 diabetes [6][8], and psychiatric disorders including depression [1][8][10]. Although research needs to expand to identify the specific function of particular strains, probiotics are collectively known to help with essential functions in the body [1][8].
Different species of microorganisms form a microecology within our body that is essential in holistic wellness. PureNature PROBIO40 contains 40 billion probiotics (beneficial live bacteria) to enhance your gut microbiome. The strains of bacteria in our formula belong to two of the most studied genera of microorganisms (Lactobacillus spp. and Bifidobacterium spp.) because of their role in food fermentation and probiotic property [3].
“Probiotic Lactobacillus species have been implicated in a variety of beneficial roles for the human body, including maintenance of the normal intestinal microbiota, pathogen interference, exclusion and antagonism, immunostimulation and immunomodulation, anticarcinogenic and antimutagenic activities, deconjugation of bile acids, and lactase release in vivo” [9: 358].
Clinical data demonstrate the probiotic effect of the species Lactobacillus acidophilus and Bifidobacterium lactic [3: 81]. The species Lactobacillus plantarum is acknowledged for its utility in sugar transport and gene encoding in the body [4]. Lactobacillus paracasei is also a known probiotic bacteria typically used in yogurt, a product with acknowledged health benefits [5].
PROBIO40 contains the following strains of above-mentioned species of probiotics:
• Lactobacillus acidophilus (L-14)
• Bifidobacterium lactis (BI-04)
• Lactobacillus plantarum (Lp-115)
• Lactobacillus paracasei (LpC-37)
PROBIO40 utilizes MAKTREK Bi-Pass Technology to prevent the destruction of probiotics by stomach acid. This is achieved by placing live bacteria in acid-resisting capsules with seaweed extract (marine polysaccharide complex). This delivery system ensures that probiotics stay alive and potent. Only living probiotics are capable of performing metabolic, anti-inflammatory, and antioxidant side effects.
We are confident about the quality of our products and offer our customers a 1-year full refund. If you are unsatisfied with your purchase, do not hesitate to reach out to our 24/7 customer service by dialing 1-888-457-6441. We have dedicated PureNature customer service agents to address your concerns.
Does PROBIO40 contain natural ingredients?
Yes! This formula is composed of natural live bacterias (i.e., probiotics).
What is the recommended dose for PROBIO40?
Take 2 capsules daily, 20-30 minutes before your meals with a full glass of water.
What are the benefits of PROBIO40?
PROBIO40 is formulated to support gastrointestinal function by promoting a healthy microbiome. This interaction also benefits other systems in the body.
What is PROBIO40's return policy?
PureNature offers a 1-year (365 days) full refund from the date of purchase. We have a 24/7 customer service to assist our customers with any concerns. Please contact 1-888-457-6441 with any questions.
The human body hosts a colony of beneficial bacteria that is responsible for many essential physiological processes. A destabilized microbiome leads to the development of various physical disorders and diseases that typically manifest in the gastrointestinal system. To boost, protect, and promote your body's microbiome, PROBIO40 delivers 40 billions counts of probiotics from Lactobacillus and Bifidobacterium species.
PROBIO40 is packed with probiotics that:
The human body hosts a colony of beneficial bacteria that is responsible for many essential physiological processes. A destabilized microbiome leads to the development of various physical disorders and diseases that typically manifest in the gastrointestinal system. To boost, protect, and promote your body's microbiome, PROBIO40 delivers 40 billions counts of probiotics from Lactobacillus and Bifidobacterium species.
PROBIO40 is packed with probiotics that:
References Cited
There are numerous scientific papers on the benefits of Probiotics. We have compiled some of the literature for your convenience.
[1] Biedermann, L., and Gerhard Rogler. 2015. The intestinal microbiota: Its role in health and disease. European Journal of Pediatrics 174(2): 151-167.
[3] Kailasapathy, K., and Chin, J. (2000) Survival and Therapeutic Potential of Probiotic Organisms with Reference to Lactobacillus acodp[hilus and Bifidobacterium spp. Immunology and Cell Biology 78:80-88.
[4] Kleerebezem, M., Boekhorst, J., van Kranenburg, R., Molenaar, D., Kuipers, O.P., Leer, R., Tarchini, R., Peters, S.A., Sandbrink, H.M., Fiers, M.W. E. J., Stiekema, W., Lankhorst R.M.K., Bron, P.A., Hoffer, S.M., Groot, M.N. N., Kerkhoven, R., de Vries, M., Ursing, B., de Vos, W.M., and Siezen, R.J. (2003). Complete genome sequence of Lactobacillus plantarum WCFS1. PNAS 100 (4) 1990-1995. https://doi.org/10.1073/pnas.0337704100.
[5] Kristo, E., Biliaderis, C.G., Tzanetakis, N. (2003). Modeling of rheological, microbiological and acidification properties of a fermented milk product containing a probiatic strain of Lactobacillus paracasei. International Dairy Journal 12: 517-528. doi:10.1016/S0958-6946(03)00074-8.
[6] Nagpal, R, Kumar, A., Kumar, M., Behare, P.V. Jain, S. and Yadav, H. 2011. Probiotics, their health benefits and application for developing healthier foods: a review. FEMS Microbiology 333(1): 1-15.
[8] Thushara, R.M., Gangadaran, S, Solati, Z., and Moghadasian, M.H. 2016. Cardiovascular benefits of probiotics: a review of experimental and clinical studies. Food Funct 7(2):632-42. doi: 10.1039/c5fo01190f.
Disclaimer: †The information on this site has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Results in description and Testimonials may not be typical results and individual results may vary. All orders placed through this website are subject to acceptance, in its sole discretion.
**Individual Results May Vary. Results in testimonials are atypical and results will vary on individual circumstances. We recommend all products with a healthy diet & exercise.